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Regenerative medicine

Head of the Center: Professor of the Department of Genetics, IFMB KFU, Leading Scientist , Head of the RSL “Genetic and Cell Technologies” Albert Rizvanov;

Scientific adviser:  head of StrAU “Translational 7P Medicine”, director of IFMB KFU, professor Andrey Pavlovich Kiyasov.

 

The structure of the Center of excellence “Regenerative medicine” includes:

RSL “Gene and cell technologies”

Research is conducted in several main areas:

– development of methods of gene and cell therapy for regenerative medicine;

– research of humoral and cell immunity in viral infections, autoimmune and communicable diseases;

– research in the field of oncology;

–   the development of new drugs based on the “target-ligand” system.

 

 

RSL “Bioactive polymers and peptides”, project “Peptide”

Head: Timur Abdullin, Ph.D. associate Professor of biochemistry and biotechnology IFMB KFU, h-index = 7

The laboratory conducts interdisciplinary research and development within priority areas of Kazan Federal University “Biomedicine and pharmaceutics”. The main scientific directions of the laboratory are:

□ systems of drug delivery;

□ synthetic and natural bioactive peptides;

□ medical supplies.

Laboratory implements a number of fundamental and applied projects with foreign universities and the leading Russian medical centers. Key partners of the laboratory are: the University of Brighton (UK), Budapest University of technology and Economics (Hungary), Republican clinical hospital (Kazan), Institute of surgery named after A. Vishnevsky (Moscow). Projects are implemented in cooperation with innovative company OOO “Biomedtech KFU”, created with the participation of Kazan Federal University.

 

 

“Microbial biotechnologies”

Head: Margarita Sharipova, Ph.D, professor, h index = 9, professor, Department of Microbiology, IFM & B KFU

The laboratory conducts studies on the pathogenesis and antibiotic resistance of Enterobacteria Salmonella and Serratia, studies are carried out to study the genetic basis of the homeostasis of human and plant cells that affect the individual rate of cell aging, predisposition to cancer and other diseases, and resistance to stress.

Scope of the laboratory: biology of aging, bioreactors, genetic engineering, molecular genetics, genomics and genoinformatics, physiology and biochemistry of microorganisms, microbial biotechnology.

 

“Protein-cell interactions”

Head: Rustem I. Litvinov, Professor, Department of biochemistry and biotechnology, KFU (h-index – 24), Department of Cell Biology, Medical Faculty, University of Pennsylvania (Philadelphia, USA), Head of KFU-RASA Center “Translational Medicine”

The research topic in 2016-2017 refers to the translational medicine, which develops practical applications based on the achievements of fundamental science. The laboratory specializes in solving the problem of thrombosis – one of the most urgent in clinical medicine.

The main project:

Project 1: Predicting and diagnosis of prethrombotic conditions and thrombosis in autoimmune diseases;

Project 2: Cellular composition of thrombs and violation of remodeling (contraction) of blood clots in thrombotic conditions.

 

“Addictive technologies in medicine”

Head: Nail Kashapov, Ph.D, Technical Sciences, Professor, Corresponding Member of the Academy of Sciences of the Republic of Tatarstan and the Russian Academy of Engineering Sciences, Honored Inventor of the Republic of Tatarstan

Development of the foundations of technologies for the additive formation of three-dimensional structures for solving urgent problems of medicine.

In the course of the work, it is planned to: develop new approaches to treatment using modern rapid prototyping technologies. With reference to the creation of biocompatible and bioresorbable composite materials.

 

The following scientific works are carried out in the laboratory:

1.Development of methods for treating head and neck tumors using 3D-prototyping technologies.

2.Development of methods for the treatment of endonasal surgery of skull base diseases, transcranial surgery of brain tumors using 3D prototyping.

3.Construction, calculation and 3D prototyping of end-to-end dental implants with reinforced internal stiffeners.

4.Development of composite powder for the additive production of a component of implants with antibacterial properties.

 

“Combinatorial chemistry and neurobiology,” the project “Neurodegeneration”

Head: Aleksei A. Belogurov, PhD, head of the group “Molecular mechanisms of autoimmune neurodegeneration”;

Scientific adviser: PhD, Professor, Academician of the Russian Academy of Sciences Alexander Gabibov, (h-index 22, Institute of Bioorganic Chemistry RAS, Russia).

Subject: Investigation of the molecular basis of neurodegenerative diseases.

 

 

 

Bionanotechnology, the project “Nanolab”

Leader:  Ph.D, associate Professor of microbiology department of KFU (h-index-22) Ravil Fakhrullin;

The laboratory conducts research on the design of new biological and biocompatible materials for their use as a carrier of drugs, modification of surfaces and modification of living cells for obtaining their images with the help of microscopic and spectroscopic techniques. The laboratory develops microscopic containers; multilayer thin films; biosensors and artificial multicellular systems. To modify the functionality of biomaterials, various nanomaterials (nanoparticles, nanofibers, etc.) are widely used. The laboratory carries out studies on the toxicity of nanomaterials, and a wide range of experimental models is used. One of the latest directions of research is the development of new delivery methods and the ordered spatial arrangement of magnetic cyborg cells for cell therapy and tissue engineering.